DS-1040 tosylate
CAS No. 1335138-89-0
DS-1040 tosylate ( DS 1040;DS1040 )
产品货号. M11340 CAS No. 1335138-89-0
DS-1040 tosylate (DS1040)is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥6464 | 有现货 |
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100MG | ¥11016 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称DS-1040 tosylate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述DS-1040 tosylate (DS1040)is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
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产品描述DS-1040 tosylate (DS1040)is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile.Stroke Phase 2 Clinical
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同义词DS 1040;DS1040
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通路Others
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靶点Other Targets
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受体Other Targets
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研究领域Neurological Disease
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适应症Stroke
化学信息
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CAS Number1335138-89-0
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分子量465.61
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分子式C23H35N3O5S
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纯度>98% (HPLC)
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溶解度——
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SMILESCC1CCC(CC1)N2C=C(N=C2)CC(CCCN)C(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O
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化学全称(S)-5-amino-2-((1-((1r,4S)-4-methylcyclohexyl)-1H-imidazol-4-yl)methyl)pentanoic acid compound with 4-methylbenzenesulfonic acid (1:1)
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971.
2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081.
3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282.
2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081.
3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282.
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